"Dr. Gabriele Casirati is awarded the ISSNAF Paola Campese Award for his exceptional achievements as a young physician-scientist and the clinical potential of his innovative research. He developed a gene-editing approach to introduce precise amino acid changes in healthy hematopoietic stem cells, improving their use in transplantation. His work addresses the challenges of acute myeloid leukemia (AML), a resistant hematological malignancy, by focusing on epitope editing of stem cells. This approach enhances chimeric antigen receptor (CAR) T-cell therapy against leukemic cells while protecting normal precursors essential for blood production, reducing treatment toxicity."
Dr. Gabriele Casirati, Researcher Fellow at the Dana Farber Cancer Institute - Boston Children's Hospital is the recipient of the 2024 YI Paola Campese Award with his outstanding research on "Epitope editing to enable targerted immunotherapy of Acute Myloid Leukemia".
Established by Stefania and Vito Campese in 2011, this award is in memory of their young, talented and generous daughter Paola.
Find more about Dr. Casirati and other Young Investigator Awadees.